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2009, discovery of a completely new phenotype for microbes in narrow nanofluidic slits; and initial detection of nearby protein structures along DNA utilizing sound-condition nanoporesThis issue is for screening if you are a human visitor and to avoid automatic spam submissions.
Within the very same time, the group of Paul McEuen, who was then centered with the University of California, Berkeley, confirmed equivalent results on ropes of bundled nanotubes. Depending upon the wrapping angle, nanotubes can can be found in metallic or semiconducting variants, a prediction that we and Charles Lieber’s group at Harvard College independently confirmed working with scanning tunnelling spectroscopy experiments.
Non-equilibrium folding of particular person DNA molecules recaptured nearly 1000 situations in the stable point out nanopore
2010, produced a whole new way (‘wedging transfer’) to govern nanostructures; to start with report of DNA translocation via graphene nanopores; and realized hybrid nanopores by directed insertion of α-hemolysin into reliable-condition nanopores
Microbiology has only existed for just a century, since we started to research micro-organisms a lot more significantly. I believed nanobiology was an ideal time period, since all molecular biological pertinent interactions happen with the nanoscale: a protein is some nanometres in dimensions, DNA is two nm thick.’
Several relevant developments followed, the place our team recognized unique transistor variants which include one-electron transistors at room temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled multiple transistors into tiny proof-of-principle electronic circuits.
Finding out DNA loop extrusion by SMC proteins for chromosome architecture with one-molecule assays.
Understanding fundamental procedures regulating the spatial and dynamic organisation of the DNA in live cells.
Dekker started off his investigation on single carbon nanotubes in 1993 when he arrange a different line of analysis to study electrical transportation via one natural molecules between nanoelectrodes. In 1996 a breakthrough was recognized with carbon nanotubes. This was accomplished inside of a collaboration Together with the group of Nobel laureate Richard Smalley. STM and nanolithography tactics had been accustomed to demonstrate that these nanotubes are quantum wires at the single-molecule stage, with excellent Actual physical Qualities.
Given that 2000 he moved to single-molecule biophysics and nanobiology, with exploration from scientific studies of DNA loop extrusion and supercoiling to DNA translocation via nanopores. Additional not too long ago his research has focused on finding out chromatin construction and mobile division with microorganisms on chip, although he is also seeking to in the end build artificial cells from the bottom up.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij met enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart design in 2005. (nl)